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Electromagnetism & Morphogenesis
Fields guiding the positioning of organelles in cells, cells in organs and organs in bodies

Pablo Andueza Munduate

This section explores the role of electromagnetic fields (EMFs) in regulating morphogenesis and cellular behavior, focusing on experimental evidence and theoretical frameworks that support an electromagnetic theory of life. The listed papers highlight how EMFs influence developmental processes, tissue organization, and intercellular communication. ...

Key findings include the generation of coherent oscillations by centrosomes and microtubules, which guide cell division and differentiation, as well as the capacity of biofilms to use EM-based communication for long-range signaling. Additionally, the relationship between morphogenetic fields and consciousness is discussed as a side note, emphasizing how form and structure serve as the physical substrate for expressing life's "to be" quality.

1. Bioelectric Fields in Morphogenesis 

  • Key Points :

    • Bioelectric communication among cells plays a critical role in shaping tissues and organs (Manicka & Levin, 2025).
    • Resting membrane potentials (Vmem) within tissues contribute to spatiotemporal patterns that regulate complexity, dimensionality, and causality (Levin, 2023).
    • External electric fields can halt or reverse morphogenesis in organisms like Hydra, demonstrating the instructive role of EM fields in development (Braun & Ori, 2019).
     
  • Significance :
    • Provides mechanisms for how EM fields guide morphological processes.
    • Links bioelectric dynamics with fundamental biological phenomena such as regeneration and cancer suppression.

2. Centrosomes and Microtubules as EM Generators 

  • Key Points :

    • Centrosomes act as geometry organizers through their electrostatic properties, influencing cell orientation and division (Regolini, 2019).
    • Microtubules generate electromagnetic waves and exhibit features of both synchronization and swarming, contributing to long-range intercellular communication (Pietak, 2012; Tuszynski, 2019).
    • Mechanical buckling of microtubules coupled with their inherent chromophore characteristics enhances resonant signaling (Tassinari et al., 2021).
     
  • Significance :
    • Demonstrates the importance of intracellular structures in generating EM fields.
    • Proposes microtubules as key players in orchestrating morphogenetic processes.

3. EM Fields in Embryogenesis and Regeneration 

  • Key Points :

    • Genome-wide analysis reveals conserved transcriptional responses downstream of changes in resting potential, indicating EM fields regulate gene expression (Pai et al., 2015).
    • Endogenous bioelectric networks store non-genetic patterning information, enabling precise control over developmental trajectories (Levin, 2014).
    • Calcium oscillations coordinate mesenchymal cell movement during feather formation, suggesting EM fields modulate gap junction networks (Li et al., 2018).
     
  • Significance :
    • Highlights the dual role of EM fields in regulating genetic and epigenetic processes.
    • Offers insights into how EM fields encode positional information during development.

4. Morphogenetic Fields and Environmental Interactions 

  • Key Points :

    • Morphogenetic fields interact with environmental cues, including Schumann resonances, to influence biological rhythms and growth patterns (Ho, 2013).
    • Plants exhibit structural evidence for electromagnetic resonance, using EM fields to guide vascular pattern formation (Pietak, 2012).
    • Electric fields in salamanders and other regenerating species create gradients that steer molecules to healing areas (Summhammer, 2021).
     
  • Significance :
    • Explores the ecological context of morphogenetic fields.
    • Suggests that EM fields may act as universal signals across species and environments.

5. EM Fields in Cellular Self-Organization 

  • Key Points :

    • Cells generate endogenous EM fields that regulate their internal and external behaviors, ensuring proper function and adaptation (Liboff, 2004; Funk et al., 2008).
    • Long-range EM interactions drive protein-protein approaches, enabling selective binding and reducing randomness in crowded cellular environments (Niccolai et al., 2022).
    • Stochastic resonance occurs when weak periodic signals interact with cellular noise, enhancing signal detection and processing (Kruglov et al., 2023).
     
  • Significance :
    • Explains how EM fields facilitate self-organization and adaptability in living systems.
    • Proposes stochastic resonance as a mechanism for amplifying weak but meaningful signals in biology.

6. Synchronization and Coordination of Cells 

  • Key Points :

    • Networks of non-excitable cells synchronize bioelectric oscillations, forming collective patterns essential for multicellular coordination (Cervera et al., 2019).
    • Gap junctional blockade induces stochastic changes in head anatomy, revealing the plasticity of bioelectric regulation (Emmons-Bell et al., 2015).
    • Cellular electric fields emerge independently of DNA, carrying ontogenetic information that guides tissue formation (Wells, 2014).
     
  • Significance :
    • Emphasizes the importance of collective bioelectric activity in multicellular systems.
    • Challenges traditional views by proposing bioelectric fields as independent carriers of developmental information.

7. Practical Applications in Medicine and Biotechnology 

  • Key Points :

    • Charge-balanced electrical stimulation modulates neural precursor cell migration, offering therapeutic potential for brain repair (Iwasa et al., 2019).
    • Endogenous electric fields guide cell migration in vivo, providing targets for interventions in wound healing and tissue engineering (Funk, 2015).
    • Bioelectric signaling regulates size in zebrafish fins, demonstrating its role in maintaining proper proportions during growth (Perathoner et al., 2014).
     
  • Significance :
    • Opens avenues for developing novel treatments based on EM field modulation.
    • Encourages integration of EM principles into regenerative medicine and biotechnology.

8. Morphogenetic Fields and Consciousness 

  • Key Points :

    • Morphogenetic fields can be seen as part of broader conscious fields, where form and structure reflect the physical expression of life's essence (Thorp, 2021).
    • EM fields generated by living systems resonate with external environmental fields, creating nested hierarchies of consciousness (Young et al., 2022).
    • General Resonance Theory (GRT) suggests that shared resonance chains allow simpler forms of consciousness to combine into more complex entities (Hunt & Schooler, 2019).
     
  • Significance :
    • Links morphogenesis with consciousness, proposing that form arises from conscious EM interactions.
    • Expands the scope of EM theories to include metaphysical and philosophical perspectives.

9. Heart and Brain EM Fields in System-Wide Order 

  • Key Points :

    • The heart generates the strongest EM field in the body, encoding emotional and physiological information through interference patterns (McCraty et al., 2009).
    • Brain oscillations synchronize with heart rhythms, creating system-wide coherence that influences cognitive and emotional states (Ross et al., 2015).
    • Heart rate variability (HRV) reflects the interaction between the heart's EM field and external geomagnetic fields, impacting overall well-being (Alabdulgader, 2021).
     
  • Significance :
    • Demonstrates the importance of the heart's EM field in maintaining systemic coherence.
    • Highlights the bidirectional relationship between internal and external EM fields in regulating health and consciousness.

10. Evolutionary Preservation of EM Patterns 

  • Key Points :

    • Evolution has preserved specific EM field patterns across species, suggesting their importance in survival and adaptation (Buzsáki et al., 2013).
    • Frequency-specific contributions of EM fields to cognitive performance indicate a conserved mechanism for information processing (Allen et al., 2018).
    • EM fields generated by centrosomes and microtubules play pivotal roles in evolutionary processes, including symmetry breaking and field-to-protein interactions (Pokorný et al., 2011).
     
  • Significance :
    • Supports the idea that EM fields are evolutionarily conserved and essential for life.
    • Links EM field dynamics with fundamental evolutionary processes like symmetry breaking.

11. Theoretical Frameworks and Future Directions 

  • Key Points :

    • Field-mediated bioelectric prepatterning models explain how EM fields regulate morphogenesis computationally (Manicka & Levin, 2025).
    • Multiscale memory and bioelectric error correction mechanisms suggest that EM fields maintain stability across developmental stages (Fields & Levin, 2017).
    • Novel hypotheses propose decoding EM field signatures associated with specific developmental events, such as Ca²⁺ oscillations (Smedler & Uhlen, 2014).
     
  • Significance :
    • Provides robust theoretical constructs for understanding EM-based morphogenesis.
    • Calls for further research into deciphering the "bioelectric code" and its implications for life and consciousness.

References

  1. Manicka, S., & Levin, M. (2025). Field-mediated Bioelectric Basis of Morphogenetic Prepatterning: A Computational Study [preprint].
  2. Elson, E. C. (2024). Embryo Development in a Stochastic Universe.
  3. Levin, M. (2023). Bioelectric Networks: The Cognitive Glue Enabling Evolutionary Scaling from Physiology to Mind.
  4. Nunn, A. V. W., Bell, G. J. D., & Guy, W. (2022). Bioelectric Fields at the Beginnings of Life.
  5. Tassinari, R., Cavallini, C., Olivi, E., Taglioli, V., Zannini, C., & Ventura, C. (2021). Unveiling the Morphogenetic Code: A New Path at the Intersection of Physical Energies and Chemical Signaling.
  6. Thorp, K. E. (2021). Morphogenic Fields: A Coming of Age.
  7. Braun, E., & Ori, H. (2019). Electric-Induced Reversal of Morphogenesis in Hydra.
  8. Cervera, J., Pai, V. P., Levin, M., & Mafe, S. (2019). From Non-Excitable Single-Cell to Multicellular Bioelectrical States Supported by Ion Channels and Gap Junction Proteins: Electrical Potentials as Distributed Controllers.
  9. Tuszynski, J. A. (2019). The Bioelectric Circuitry of the Cell.
  10. Iwasa, S. N., Rashidi, A., Sefton, E., Liu, N. X., Popovic, M. R., & Morshead, C. M. (2019). Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains.
  11. Pietak, A. M. (2010). Endogenous Electromagnetic Fields in Plant Leaves: A New Hypothesis for Vascular Pattern Formation.
  12. Pietak, A. M. (2012). Structural Evidence for Electromagnetic Resonance in Plant Morphogenesis.
  13. Pietak, A. M. (2013). Living Energy Resonators: Transcending the Gene to a New Story of Light and Life.
  14. Tseng, A., & Levin, M. (2013). Cracking the Bioelectric Code: Probing Endogenous Ionic Controls of Pattern Formation.
  15. Guo, A., Song, B., Reid, B., Gu, Y., Forrester, J. V., Jahoda, C. A. B., & Zhao, M. (2010). Effects of Physiological Electric Fields on Migration of Human Dermal Fibroblasts.
  16. Levin, M. (2003). Bioelectromagnetics in Morphogenesis.
  17. Wells, J. (2014). Membrane Patterns Carry Ontogenetic Information That Is Specified Independently of DNA.
  18. Fields, C., & Levin, M. (2017). Multiscale Memory and Bioelectric Error Correction in the Cytoplasm-Cytoskeleton-Membrane System.
  19. Funk, R. H. W. (2015). Endogenous Electric Fields as Guiding Cue for Cell Migration.
  20. Cao, L., Wei, D., Reid, B., Zhao, S., Pu, J., Pan, T., Yamoah, E., & Zhao, M. (2013). Endogenous Electric Currents Might Guide Rostral Migration of Neuroblasts.
  21. Li, A., Cho, J.-H., Reid, B., Tseng, C.-C., He, L., Tan, P., Yeh, C.-Y., Wu, P., Li, Y., Widelitz, R. B., Zhou, Y., Zhao, M., Chow, R. H., & Chuong, C.-M. (2018). Calcium Oscillations Coordinate Feather Mesenchymal Cell Movement by SHH Dependent Modulation of Gap Junction Networks.
  22. Pai, V. P., Martyniuk, C. J., Echeverri, K., Cruz, S. S., Kaplan, D. L., & Levin, M. (2015). Genome-Wide Analysis Reveals Conserved Transcriptional Responses Downstream of Resting Potential Change in Xenopus Embryos, Axolotl Regeneration, and Human Mesenchymal Cell Differentiation.
  23. Pietak, A. M. (2015). Electromagnetic Resonance and Morphogenesis.
  24. Lobikin, M., & Levin, M. (2015). Endogenous Bioelectric Cues as Morphogenetic Signals in Vivo.
  25. Emmons-Bell, M., Durant, F., Hammelman, J., Bessonov, N., Volpert, V., Morokuma, J., Pinet, K., Adams, D. S., Pietak, A., Lobo, D., & Levin, M. (2015). Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia Dorotocephala Flatworms.
  26. Hubacher, J. (2015). The Phantom Leaf Effect: A Replication (Part 1).
  27. Summhammer, J. (2021). Morphology and High-Frequency Bio-Electric Fields.
  28. Perathoner, S., Daane, J. M., Henrion, U., Seebohm, G., Higdon, C. W., Johnson, S. L., Nüsslein-Volhard, C., & Harris, M. P. (2014). Bioelectric Signaling Regulates Size in Zebrafish Fins.
  29. Tyler, S. E. B. (2014). The Work Surfaces of Morphogenesis: The Role of the Morphogenetic Field.
  30. Cifra, M. (2012). Electrodynamic Eigenmodes in Cellular Morphology.
  31. Iwasa, S. N., Babona-Pilipovs, R., & Morshead, C. M. (2017). Environmental Factors That Influence Stem Cell Migration: An "Electric Field".
  32. Ho, M.-W. (2013). Life is Water Electric.
  33. Detmar, C. F. (2022). An Adaptational Theory of Consciousness.
  34. Keppler, J. (2021). Building Blocks for the Development of a Self-Consistent Electromagnetic Field Theory of Consciousness.
  35. McFadden, J. (2020). Integrating Information in the Brain’s EM Field: The CEMI Field Theory of Consciousness.
  36. Jones, M. W. (2016). Mounting Evidence That Minds Are Neural EM Fields Interacting with Brains.
  37. Khrennikov, A. (2010). Quantum-Like Model of Processing of Information in the Brain Based on Classical Electromagnetic Field.
  38. Wnuk, M. J., & Bernard, C. D. (2001). The Electromagnetic Nature of Life - The Contribution of W. Sedlak to the Understanding of the Essence of Life.
  39. Jones, M. W. (2019). Growing Evidence That Perceptual Qualia Are Neuroelectrical Not Computational.
  40. Hales, C. G., & Ericson, M. (2022). Electromagnetism’s Bridge Across the Explanatory Gap: How a Neuroscience/Physics Collaboration Delivers Explanation Into All Theories of Consciousness.
  41. McCraty, R., Atkinson, M., Tomasino, D., & Bradley, R. T. (2009). The Coherent Heart: Heart–Brain Interactions, Psychophysiological Coherence, and the Emergence of System-Wide Order.

Keywords

  • Electromagnetic Fields (EMFs), Morphogenesis, Bioelectricity, Centrosomes, Microtubules, Synchronization, Regeneration, Consciousness, Panpsychism, Fractal Dynamics, Quantum Effects, Neural Precursor Cells, Gap Junctions, Epigenetic Regulation
-Text generated by AI superficially, for more specific but also more surprising data check the tables below-

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text updated (AI generated): 11/02/2025
tables updated (Human): 27/01/2025

Endogenous Fields & Mind
EM & Morphogenetics

Endogenous Electromagnetism & Morphogenesis

(F) Full or (A) Abstract

Available Formats

Title

Commentary

Publication Year (and Number of Pages)

Author(s)
Favailable in PDFField-mediated Bioelectric Basis of Morphogenetic Prepatterning: a computational study [preprint]Commentary icon2025-(34)Santosh Manicka, Michael Levin
Aavailable in HTMLEmbryo Development in a Stochastic UniverseCommentary icon2024-(1)Edward C. Elson
F
available in PDF and HTMLBioelectric networks: the cognitive glue enabling evolutionary scaling from physiology to mindCommentary icon2023-(27)Michael Levin
Favailable in PDF, HTML and EpubBioelectric Fields at the Beginnings of LifeCommentary icon2022-(11)Alistair V. W. Nunn, Geoffrey W. Guy, Jimmy D. Bell
Favailable in PDF and HTMLUnveiling the morphogenetic code: A new path at the intersection of physical energies and chemical signalingCommentary icon2021-(13)Riccardo Tassinari, Claudia Cavallini, Elena Olivi, Valentina Taglioli, Chiara Zannini, Carlo Ventura
Favailable in PDFMorphology and high frequency bio-electric fieldsCommentary icon2021-(17)Johann Summhammer
Aavailable in HTMLMorphogenic Fields: A Coming of AgeCommentary icon2021-(1)K. E. Thorp
Favailable in PDF and HTMLElectric-Induced Reversal of Morphogenesis in HydraCommentary icon2019-(10)Erez Braun, Hillel Ori
Aavailable in HTMLFrom non-excitable single-cell to multicellular bioelectrical states supported by ion channels and gap junction proteins: Electrical potentials as distributed controllersCommentary icon2019-(1)Javier Cervera, Vaibhav P. Pai, Michael Levin, Salvador Mafe
Aavailable in HTMLThe Centrosome as a Geometry OrganizerCommentary icon2019-(1)Marco Regolini
Aavailable in HTMLSynchronization of Bioelectric Oscillations in Networks of Non-Excitable Cells: From Single-Cell to Multicellular StatesCommentary icon2019-(1)Javier Cervera, Jose Antonio Manzanares, Salvador Mafe, Michael Levin
Favailable in PDF and HTMLCalcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networksCommentary icon2018-(15)Ang Li, Jung-Hwa Cho, Brian Reid, Chun-Chih Tseng, Lian He, Peng Tan, Chao-Yuan Yeh, Ping Wu, Yuwei Li, Randall B. Widelitz, Yubin Zhou, Min Zhao, Robert H. Chow, Cheng-Ming Chuong
Favailable in PDF and HTMLGenome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiationNo comments yet icon2015-(23)Vaibhav P. Pai, Christopher J. Martyniuk, Karen Echeverri, Sarah Sundelacruz, David L. Kaplan, Michael Levin
Favailable in PDFElectromagnetic resonance and morphogenesisNo comments yet icon2015-(18)Alexis Mari Pietak
Favailable in PDFEndogenous bioelectric cues as morphogenetic signals in vivoNo comments yet icon2015-(20)Maria Lobikin, Michael Levin
Favailable in PDF and HTMLEndogenous Gradients of Resting Potential Instructively Pattern Embryonic Neural Tissue via Notch Signaling and Regulation of ProliferationNo comments yet icon2015-(20)Vaibhav P.Pai, Joan M. Lemire, Jean-Francois Pare, Gufa Lin, Ying Chen, Michael Levin
Favailable in PDF and HTMLGap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala FlatwormsNo comments yet icon2015-(32)Maya Emmons-Bell, Fallon Durant, Jennifer Hammelman, Nicholas Bessonov, Vitaly Volpert, Junji Morokuma, Kaylinnette Pinet, Dany S. Adams, Alexis Pietak , Daniel Lobo, Michael Levin
Aavailable in HTMLThe phantom leaf effect: A replication (Part 1)Commentary icon2015-(1)John Hubacher
Favailable in PDFMembrane Patterns Carry Ontogenetic Information That Is Specified Independently of DNANo comments yet icon2014-(38)Jonathan Wells
Favailable in PDF and HTMLBioelectric Signaling Regulates Size in Zebrafish FinsNo comments yet icon2014-(11)Simon Perathoner, Jacob M. Daane, Ulrike Henrion, Guiscard Seebohm, Charles W. Higdon, Stephen L. Johnson, Christiane Nüsslein-Volhard, Matthew P. Harris
Favailable in PDF and HTMLEndogenous bioelectrical networks store non-genetic patterning information during development and regenerationNo comments yet icon2014-(11)Michael Levin
Aavailable in HTMLThe Work Surfaces of Morphogenesis: The Role of the Morphogenetic FieldNo comments yet icon2014-(1)Sheena E. B. Tyler
Favailable in PDF, HTML and EpubCracking the bioelectric code: Probing endogenous ionic controls of pattern formationNo comments yet icon2013-(8)AiSun Tseng, Michael Levin
Favailable in PDFLiving Energy Resonators: Transcending the Gene to a New Story of Light and LifeNo comments yet icon2013-(4)Alexis Mari Pietak
Favailable in PDFStructural evidence for electromagnetic resonance in plant morphogenesisCommentary icon2012-(14)Alexis Mari Pietak
Favailable in PDFBiomechanical and coherent phenomena in morphogenetic relaxation processesNo comments yet icon2012-(10)Abir U. Igamberdiev
Favailable in PDFMorphogenetic fields in embryogenesis, regeneration, and cancer: Non-local control of complex patterningNo comments yet icon2012-(19)Michael Levin
Aavailable in HTMLElectrodynamic eigenmodes in cellular morphologyCommentary icon2012-(1)M. Cifra
Favailable in PDFEndogenous Electromagnetic Fields in Plant Leaves: A New Hypothesis for Vascular Pattern FormationNo comments yet icon2010-(32)Alexis Mari Pietak
Favailable in PDFBioelectromagnetics in MorphogenesisNo comments yet icon2003-(21)Michael Levin
 At the cellular level:
Favailable in PDF and HTMLElectrochemical gradients are involved in regulating cytoskeletal patterns during epithelial morphogenesis in the Drosophila ovaryNo comments yet icon2019-(17)Isabel Weiß, Johannes Bohrmann
Favailable in PDF and HTMLThe Bioelectric Circuitry of the CellCommentary icon2019-(14)Jack A. Tuszynski
Favailable in PDFMultiscale Memory And Bioelectric Error Correction In The Cytoplasm-Cytoskeleton-Membrane SystemCommentary icon2017-(30)Chris Fields, Michael Levin
 On cell migration:
Favailable in PDF and HTMLCharge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse BrainsCommentary icon2019-(42)Stephanie N. Iwasa, Abdolazim Rashidi, Elana Sefton, Nancy X. Liu, Milos R. Popovic, Cindi M. Morshead
Favailable in PDF, HTML and EpubEnvironmental Factors That Influence Stem Cell Migration: An “Electric Field”Commentary icon2017-(1)Stephanie N. Iwasa, Robart Babona-Pilipos, Cindi M. Morshead
Aavailable in HTMLThe use of electric, magnetic, and electromagnetic field for directed cell migration and adhesion in regenerative medicineNo comments yet icon2016-(1)Christina L. Ross
Favailable in PDF, HTML and EpubEndogenous electric fields as guiding cue for cell migrationNo comments yet icon2015-(8)Richard H. W. Funk
Favailable in PDF, HTML and EpubEndogenous electric currents might guide rostral migration of neuroblastsNo comments yet icon2013-(7)Lin Cao, Dongguang Wei, Brian Reid, Siwei Zhao, Jin Pu, Tingrui Pan, Ebenezer Yamoah, Min Zhao
Favailable in PDF, HTML and EpubEffects of Physiological Electric Fields on Migration of Human Dermal FibroblastsNo comments yet icon2010-(8)Aihua Guo, Bing Song, Brian Reid ,Yu Gu, John V. Forrester, Colin A.B. Jahoda, Min Zhao

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