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Electromagnetism & Fröhlich Modes
Collective large-scale vibrational modes involving microwave absorption and emission

Pablo Andueza Munduate

Fröhlich modes represent collective electromagnetic (EM) excitations within biological systems, driven by dipolar interactions and out-of-equilibrium dynamics. This section explores the foundational principles of Fröhlich condensation and its relevance to cellular coherence, biomolecular interactions, and long-range communication. ...

This section synthesizes findings on the experimental validation of Fröhlich condensation, the influence of terahertz radiation on protein structures, and the implications of these phenomena for understanding biological coherence. The evidence underscores the importance of endogenous electromagnetic fields in orchestrating cellular processes and suggests a foundational role in biological regulation and information processing.

The concept of Fröhlich modes, first proposed in the 1960s, describes a state of coherence in biological systems far from thermal equilibrium. This theoretical framework suggests that collective oscillations in biological macromolecules, driven by metabolic energy, could lead to Bose-Einstein-like condensation in biological systems. Recent experimental studies have provided evidence supporting this hypothesis, linking Fröhlich modes to electromagnetic fields, cellular communication, and long-range coherence. This section explores these findings, emphasizing their implications for biological information processing and systemic organization.

Key Findings and Experimental Evidence:

  • Terahertz Radiation and Structural Changes in Proteins:

    • Studies on bovine trypsin crystals irradiated with 0.5 THz radiation demonstrate increased anisotropy in atomic displacements, indicating the presence of delocalized vibrational modes (Ahlberg Gagnér et al., 2019).

    • These modes, consistent with Fröhlich’s predictions, suggest a mechanism for protein-protein interactions and biochemical regulation at terahertz frequencies.

  • Quantum Fluctuations in Fröhlich Condensates:

    • Research on molecular vibrations driven far from equilibrium has identified quantum fluctuations in Fröhlich condensates. These findings highlight the potential for coherent oscillatory states to mediate long-range biological interactions (Zhang et al., 2018).

  • Out-of-Thermal Equilibrium Oscillations:

    • Experimental models using bovine serum albumin (BSA) reveal absorption features around 0.314 THz when driven into non-equilibrium states. These observations provide direct evidence for the existence of Fröhlich modes in living systems (Nardecchia et al., 2017).

Mechanisms and Implications:

  • Energy Localization and Long-Range Coherence:

    • Fröhlich modes enable the localization of vibrational energy, creating coherent states that facilitate efficient energy transfer and information processing within cells.

    • These mechanisms align with the observation of collective vibrational modes in protein structures, contributing to intracellular coordination.

  • Interaction with Endogenous Electromagnetic Fields:

    • Fröhlich modes interact with endogenous EM fields generated by metabolic activity, influencing cellular communication and systemic regulation.

    • The periodic transformations between phonons and photons in Fröhlich condensates suggest a dynamic interplay between mechanical and electromagnetic energies.

  • Biological Implications:

    • Fröhlich modes have been implicated in various biological phenomena, including protein folding, enzymatic reactions, and signal transduction.

    • Their role in coordinating long-range interactions highlights their importance in maintaining biological coherence and systemic organization.

Future Directions and Applications:

  • Terahertz Spectroscopy in Biomedical Research:

    • Advances in terahertz spectroscopy offer new tools for investigating Fröhlich modes and their role in health and disease.

    • Potential applications include disease diagnosis, understanding protein misfolding disorders, and developing terahertz-based therapeutic interventions.

  • Quantum and Biophysical Studies:

    • Further research on the quantum properties of Fröhlich modes could elucidate their role in information processing and coherence in biological systems.

Conclusion: The experimental validation of Fröhlich modes underscores their significance in biological systems. By facilitating long-range coherence and efficient energy transfer, these modes contribute to the regulation and organization of cellular processes. Their interaction with endogenous electromagnetic fields offers a compelling framework for understanding biological coherence and opens avenues for novel biomedical applications.

Keywords: Fröhlich modes, electromagnetic fields, terahertz radiation, biological coherence, protein dynamics, quantum fluctuations.

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text updated (AI generated): 23/12/2024
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Endogenous Fields & Mind
EM & Fröhlich Modes

Endogenous Electromagnetism & Fröhlich Modes

(F) Full or (A) Abstract

Available Formats

Title

Commentary

Publication Year (and Number of Pages)

Author(s)
Favailable in PDFCollective Excitations in α-helical Protein Structures Interacting with the Water Environment [preprint]No comments yet icon2020-(30)Vasiliy N. Kadantsev, Alexey Goltsov
Favailable in PDFControl of interaction of millimeter waves with biological mediaCommentary icon2019-(7)Nellu Ciobanu, Ion Grabovschi, Natalia Gubceac, Tatiana Oloinic, Vasile Tronciu
Favailable in PDF and HTMLClustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties
Commentary icon2019-(14)Viktor Ahlberg Gagnér, Ida Lundholm, Maria-Jose Garcia-Bonete, Helena Rodilla, Ran Friedman, Vitali Zhaunerchyk, Gleb Bourenkov, Thomas Schneider, Jan Stake, Gergely Katona
Favailable in PDFQuantum Fluctuations in the Fröhlich Condensate of Molecular Vibrations Driven Far From EquilibriumNo comments yet icon2019-(6)Zhedong Zhang, Girish S. Agarwal, Marlan O. Scully
Favailable in PDF and HTMLOut-of-equilibrium collective oscillation as phonon condensation in a model proteinCommentary icon2017-(16)Ilaria Nardecchia, Jeremie Torres, Mathias Lechelon, Valeria Giliberti, Michele Ortolani, Philippe Nouvel, Matteo Gori, Irene Donato, Jordane Preto, Luca Varani, James Sturgis, Marco Pettini
Favailable in PDFTowards disease diagnosis through terahertz spectroscopy of biological components and tissuesCommentary icon2017-(243)Peri Vaughan Jones
Aavailable in HTMLSemi-classical statistical description of Fröhlich condensationNo comments yet icon2017-(1)Jordane Preto
Aavailable in HTMLClassical investigation of long-range coherence in biological systemsNo comments yet icon2016-(1)Jordane Preto
Favailable in PDFBio-Soliton Model that predicts distinct non-thermal Electromagnetic Radiation Frequency Bands, that either Stabilize or Destabilize Life Conditions [preprint]No comments yet icon2016-(23)J.H. Geesink, D.K.F. Meijer
Favailable in PDFAn original theory regarding the correlations between the extremely high frequency electromagnetic waves of athermic intensities and their cellular effectsCommentary icon2015-(9)Emil Anton, Anatol Rotaru, Daniel Covatariu, Alin Ciobica, Daniel Timofte, Carmen Anton
Favailable in PDFLinks between extremely high frequency electromagnetic waves and their biological manifestationsNo
                                         comments yet icon2015-(3)Emil Anton, Anatol Rotaru, Daniel Covatariu, Alin Ciobica, Daniel Timofte, Radu Popescu, Carmen Anton
Favailable in PDF and HTMLTerahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystalNo comments yet icon2015-(13)Ida V. Lundholm, Helena Rodilla, Weixiao Y. Wahlgren, Annette Duelli, Gleb Bourenkov, Josip Vukusic, Ran Friedman, Jan Stake, Thomas Schneider, Gergely Katona
Favailable in PDFInvestigating encounter dynamics of biomolecular reactions: long-range resonant interactions versus Brownian collisionsNo comments yet icon2015-(14)Jordane Preto, Ilaria Nardecchia, Sebastien Jaeger, Pierre Ferrier, Marco Pettini
Aavailable in HTMLRadiating Fröhlich system as a model of cellular electromagnetismNo comments yet icon2014-(1)Fedor Šrobár
Aavailable in HTMLImpact of mitochondrial electric field on modal occupancy in the Fröhlich model of cellular electromagnetismNo comments yet icon2013-(1)Fedor Šrobár
Favailable in PDFNonlinear phenomena of Fröhlich phonons in biololgical mediaNo comments yet icon2013-(9)Anatol Rotaru, Nellu Ciobanu, V. Z. Tronciu
Favailable in PDFFröhlich Systems in Cellular PhysiologyNo comments yet icon2012-(10)Fedor Šrobár
Favailable in PDF and HTMLFröhlich Condensate: Emergence of Synergetic Dissipative Structures in Information Processing Biological and Condensed Matter SystemsNo comments yet icon2012-(20)Aurea R. Vasconcellos, Fabio Stucchi Vannucchi, Sérgio Mascarenhas, Roberto Luzzi
Favailable in PDF and HTMLWeak, strong, and coherent regimes of Frohlich condensation and their applications to terahertz medicine and quantum consciousnessNo comments yet icon2009-(6)Jeffrey R. Reimers, Laura K. McKemmish, Ross H. McKenzie, Alan E. Mark, Noel S. Hush
Favailable in PDFMode coupling in living systems: Implications for biology and medicineNo comments yet icon2008-(9)John Swain
Favailable in PDFCoupling of Frohlich-Modes as a Basis of Biological RegulationNo comments yet icon2007-(39)Fritz-Albert Popp

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