" Overall, this study shows spiking activity in the hippocampus can take place in the absence of synaptic transmission, electric gap junction or diffusion at a speed of about 0.1 m/s. The prevalence of non-synaptic propagation across several experimental approaches suggests that there exists a common mechanism mediating the neural signal travelling in the brain associated with the change of extracellular electrical field. Moreover, further analysis shows that source of these spikes is itself moving by a slower speed of about 0.016 m/s. Therefore, these results indicate a novel type of neural activity propagation mechanisms in the hippocampus. This could be important to explain how neural activity can be synchronized across neural tissue in both normal and abnormal conditions such as epilepsy."
Last modified on 10-Apr-18