In vivo ephaptic coupling allows memory network formation

" It is increasingly clear that memories are distributed across multiple brain areas. Such “engram complexes” are important features of memory formation and consolidation. Here, we test the hypothesis that engram complexes are formed in part by bioelectric fields that sculpt and guide the neural activity and tie together the areas that participate in engram complexes. Like the conductor of an orchestra, the fields influence each musician or neuron and orchestrate the output, the symphony. Our results use the theory of synergetics, machine learning and data from a spatial delayed saccade task and provide evidence for in vivo ephaptic coupling in memory representations." {Credits 1}

{Credits 1} 🎪 Pinotsis, D., & Miller, E. K. (2023). In vivo ephaptic coupling allows memory network formation. bioRxiv, 2023-02. © 2023 The Authors. This article is licensed under a Creative Commons Attribution International 4.0 License..