Changes in functional connectivity dynamics with aging A dynamical phase synchronization approach

" The results of surrogate analyses confirmed that the temporal dynamics of phase synchronization arise from deterministic processes in the neural network system. Group comparison showed region-specific enhanced complexity of temporal dynamics of phase synchronization in older subjects in alpha band predominantly in frontal brain regions."

" A reasonable explanation was presented by Voytek and Knight (2015). They constructed a theoretical framework in their review postulating that dynamic network communication reflects a balance between oscillatory coupling and local population spiking activity. A moderate strength of oscillatory coupling generates optimal synchrony of spike timing within the local neuronal populations, which is supported by many pathological and computational modeling studies ... They argued that alterations of this oscillatory activity are associated with aging. Further, age-related cognitive decline is reportedly associated with neural noise."

Last modified on 16-Feb-19

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