" This study suggests that ROS generated in cells may achieve its physiological and pathological effects via biophotonic emissions, which provides a new quantum biological mechanism of ROS, while the detailed clarification requires further research." {Credits 1} " Although a large number of studies as demonstrated above have shown that ROS affect cell growth, proliferation, differentiation and apoptosis [11 , 13 , 46] through different levels in cytoplasm or nucleus, the exact mechanism is unclear. In the present study, using different concentrations of H2O2 to act on liver tissue slices and hepatocyte nuclei, we found that H2O2 can induce biophoton emissions in a concentration-dependent manner. H2O2 at low and medium levels of concentrations (300 μM and 400 μM) can lead to the rapid increase of biophoton emissions in liver tissue slices, and then maintain stability after a slow decrease. However, such effects were only noticed at high level concentrations (500 μM) in hepatocyte nucleus since the application of the H2O2 at low and medium levels of concentrations (300 μM and 400 μM) resulted in a slow increase of biophoton emissions. Because liver tissue slices contain both cytoplasmic and nuclear contents, the pattern of biophoton emissions after application of H2O2 on liver tissue slices may be a comprehensive result of the effect on cytoplasm and nucleus, especially at the high concentration level." {Credits 1} " Although there are differences in biophoton activity patterns caused by the different concentrations of H2O2 on liver slices and hepatocyte nuclei, a common feature is that H2O2 can lead to significant biophoton emissions. Combining the effect that different levels of ROS in cytoplasm and nucleus have effects on the state of cell, we assume that ROS change the energy level of targeted molecules by radiating biophotons. The most important reason is that the time of intracellular ROS generation and degradation is very short [18], which ROS’s traditional action mode through the diffusion process of ROS molecules and the combination of targets can’t explain its mechanism." {Credits 1} {Credits 1} 🎪 Fan, R., Liu, N., & Dai, J. (2022). Biophoton Radiations Induced by Hydrogen Peroxide in Mouse Liver Slices and Hepatocyte Nuclei in Relation to the Biophysical Action Mechanism of Reactive Oxygen Species. Natural Science, 14(6), 217-225. © 2022 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License. |
Last modified on 28-Jun-22 |