Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment


" The present study assessed behavioral and histopathological consequences of exposing mice to 7.5 kHz MF at 12 or 120 μT for 5 weeks. No effects were observed on body weight, spontaneous activity, motor coordination, level of anxiety or aggression. In the Morris swim task, mice in the 120 μT group showed less steep learning curve than the other groups, but did not differ from controls in their search bias in the probe test. The passive avoidance task indicated a clear impairment of memory over 48 h in the 120 μT group. No effects on astroglial activation or neurogenesis were observed in the hippocampus. The mRNA expression of brain-derived neurotrophic factor did not change but expression of the proinflammatory cytokine tumor necrosis factor alpha mRNA was significantly increased in the 120 μT group. These findings suggest that 7.5 kHz MF exposure may lead to mild learning and memory impairment, possibly through an inflammatory reaction in the hippocampus." {Credits 1}

{Credits 1} 🎪 Kumari K, Koivisto H, Viluksela M, Paldanius KMA, Marttinen M, Hiltunen M, et al. (2017) Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment. PLoS ONE 12(12): e0188880. © 2017 Kumari et al. This work is licensed under the Creative Commons Attribution License.


Last modified on 16-Apr-20

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