Circadian rhythmicity of antioxidant markers in rats exposed to 1.8 GHz radiofrequency fields


" The results obtained in the present study indicated significantly decreased levels of Mel in rats exposed to 1.8 GHz RF compared to those in sham-exposed rats. Furthermore, among the six different groups of rats, the levels of Mel [melatonin] were significantly decreased when RF exposures were given at GMT 23:00 and 3:00 when the levels should have been at the highest: thus, the data indicated alteration in amplitude and peak phase of Mel synthesis .. The results of the present study showed decreased levels of GSH-Px [glutathione peroxidase] and SOD [superoxide dismutase] levels in rats exposed to 1.8 GHz, especially at 3:00 GMT (RF 3). In addition, the circadian rhythm of GSH-Px and SOD were disrupted in RF-exposed rats, with a distinct disorder of peak phase (from GMT 2:39 to 7:35 or from GMT 5:03 to 3:12 respectively)"


Last modified on 03-Oct-16

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