Study of genotoxic and cytotoxic effects induced in human fibroblasts by exposure to pulsed and continuous 1.6 GHz radiofrequency

" 1.6 GHz RF exposure modified proteins expression and morphology of HDF. Specifically, the expression of different heat-shock proteins (HSP) (i.e., HSP-90, HSP-60, and HSP-25) and phospho-AKT were affected. In addition, both continuous and pulsed RF modified the cytoskeletal organization in HDF and increased the number of lysosomes, while the formation of autophagosomes was observed only after pulsed RF exposure. Mitotic spindle anomalies were also found after exposure. However, no significant effect was observed on cell cycle, chromosome segregation, CREST-stained micronuclei and γ-H2AX/53BP1 foci." {Credits 1}

{Credits 1} 🎪 Massaro L, De Sanctis S, Franchini V, Regalbuto E, Alfano G, Focaccetti C, Benvenuto M, Cifaldi L, Sgura A, Berardinelli F, Marinaccio J, Barbato F, Rossi E, Nardozi D, Masuelli L, Bei R and Lista F (2024) Study of genotoxic and cytotoxic effects induced in human fibroblasts by exposure to pulsed and continuous 1.6 GHz radiofrequency. Front. Public Health. 12:1419525. doi: 10.3389/fpubh.2024.1419525. © 2024 The author(s). This article is distributed under the terms of the Creative Commons Attribution License.