Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy

First they use new technical appliance (using a SQUID device) to record the radio frequency electromagnetic field originating from a biomolecule (from the pure population of the same biomolecules in a solution): the siRNA of epidermal growth factor receptor (EGFR).

Secondly they exposed cells to this recorded electromagnetic signal, that causes cells to have a 30–70% reduction of EGFR mRNA expression and ~60% reduction in EGFR protein expression, decreased cell viability, a lactato deshidrogenasa release and Caspase 3 cleavage. So RFE signal can induce a specific siRNA-like effect on cells.

Last modified on 28-Apr-16

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