" Additional evidence that arose from the ORR analysis is that PBM may have different effects and mechanism of action depending on the previous redox state of the cells. This was shown by decreased variability in ORR values 4 h after illumination, in both cell lines, caused by a decrease in the highest and an increase in the lowest values of ORR. It suggests that PBM acts differently according to the cells. In this instance, it may be more effective to the ones that differ from the mean redox state of the population." {Credits 1} " In this study, ROS concentration increased only in SCC-25 cells, indicating that PBM acts by a different pathway in fibroblasts." {Credits 1} " Nevertheless, ATP levels were increased in both cell lines after PBM." {Credits 1} " In fact, we observed an increase in G2/M fraction for both cells at 8 and 12 h after PBM. However, it did not result in increased proliferation in the tumor cell line but did in HDFn cells." {Credits 1} {Credits 1} 🎪 Faria, C. M. G., Ciol, H., Bagnato, V. S., & Pratavieira, S. (2020). Effects of photobiomodulation on the redox state of healthy and cancer cells. bioRxiv. This is an open access article distributed under the terms of the Creative Commons Attribution license. |
Last modified on 20-Sep-20 |