Cellular transformations in near-infrared light-induced apoptosis in cancer cells revealed by label-free CARS imaging

Higher apoptosis rates are for the lower irradiation doses 0.3 J/cm2 (~58%) and 3 J/cm2 (~28%), there is not apoptosis in 10 J/cm2 and in 30 J/cm2 is increased again. After irradiation with 0.3 J/cm2 there is an apoptosis‐associated reorganization of nuclear proteins and cytoplasmic lipids. There is gradual increase in the nuclear protein level over time. Irradiarion with 0.3 J/cm2 also causes lipid droplets accumulation.