Extremely Low-Frequency Electromagnetic Fields Promote In Vitro Neuronal Differentiation and Neurite Outgrowth of Embryonic Neural Stem Cells via Up-Regulating TRPC1

" ... the expression of the proneural genes, NeuroD and Ngn1 [Neurogenin 1], which are crucial for neuronal differentiation and neurite outgrowth, was increased." {Credits 1}

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" ... the expression of transient receptor potential canonical 1 (TRPC1) was significantly up-regulated accompanied by increased the peak amplitude of intracellular calcium level." {Credits 1}

{Credits 1} 🎪 Ma, Q., Chen, C., Deng, P., Zhu, G., Lin, M., Zhang, L., … Yu, Z. (2016). Extremely Low-Frequency Electromagnetic Fields Promote In Vitro Neuronal Differentiation and Neurite Outgrowth of Embryonic Neural Stem Cells via Up-Regulating TRPC1. PloS one, 11(3), e0150923. doi:10.1371/journal.pone.0150923. © 2016 Ma et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.