Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains

" Our results support that endogenous and applied electric fields are important considerations for designing cell therapies for tissue repair in vivo." {Credits 1}

" ... Endogenous electric fields exist in the adult brain along the rostral migratory stream and disrupting them can reverse the migration direction of neural precursor cells. We demonstrate that an endogenous electric field exists on the corpus callosum which correlates with the preferred lateral migration of transplanted neural precursor cells. Endogenous electric fields in the brain provide migratory cues that can impact neural repair." {Credits 1}

{Credits 1} 🎪 Iwasa, S. N., Rashidi, A., Sefton, E., Liu, N. X., Popovic, M. R., & Morshead, C. M. (2019). Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains. eNeuro. Published under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.