Monitoring Alzheimer’s Disease via Ultraweak Photon Emission

" Pearson correlation analysis revealed that 73% of the UPE variance could be explained by MDA concentration, while 60% of the UPE variance could be explained by AChE activity of the hippocampus. In addition, studies have suggested that mitochondria can have key roles in neurogenesis ( 77; 78; 79). Increasing evidence suggests that the dysfunction of cellular organelles, particularly mitochondria, has important roles in neurodegenerative disorders ( 79). These above-mentioned results and facts support the hypothesis that perturbed redox (oxidative stress) and mitochondrial mechanisms may play key roles in the development of AD. Thus, the UPE detection of the brain may be useful for a better understanding of the development of AD, its diagnosis, and the development of possible drugs. Therefore, it is possible that a photonic chip that can efficiently detect biophotons from the hippocampus could be a tool for the diagnosis or monitoring of AD. Biophoton emissions from the brain have been suggested as a potential diagnostic marker for various neurological disorders, and here we have shown that it can include AD, in which detecting changes in biophoton emissions from the hippocampus could help monitor the progression of AD." {Credits 1}

{Credits 1} 🎪 Sefati, N., Esmaeilpour, T., Salari, V., Zarifkar, A., Dehghani, F., Khorsand Ghaffari, M., ... & Oblak, D. (2023). Monitoring Alzheimer's Disease via Ultraweak Photon Emission. bioRxiv, 2023-03. © 2023 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License.