Dynamics of Brain-Specific Proteins and Melatonin Before and After Microwave Resonance Therapy in Patients with Aftereffects of Mild Brain Injury

" The study of brain-specific proteins (S-100, MBP, EP, 3G-9-D6, GFAP) and melatonin hormone in patients with long-term effects of mild closed traumatic brain injury, before and after microwave resonance therapy was undertaken. Results: The dynamic observation of 20 patients with aftereffects of mild closed traumatic brain injury showed that microwave resonance therapy (MRT) leads to normalization of hormone melatonin and cerebrospinal proteins’ state in this group of patients." {Credits 1}

" For each patient the individual, so-called resonance therapeutic frequency of exposure, was titrated, that caused the specific sensory responses, and using a fluoroplastic waveguide the researches were placing the source of emission to the targeted biologically active point." {Credits 1}

" After MRT procedure the AAB content to proteins S-100, GFAP, and 3G-9-D6 decreased and was close to the control group indices, and the AAB content to the EP has increased, although before the treatment, this figure was three times higher than in the control group, this may indicate the prolonged neuroimmune processes against neurons and glia associated with damage to the brain blood-brain barrier in patients with CTBI. MRT reduces the activity of these reactions and balances the indicators of humoral regulation." {Credits 1}

" Against this background, an increase in melatonin level was observed, which, on the one hand, is a manifestation of a compensatory reaction, and, on the other hand, is an attempt to normalize and inhibit the inflammatory autoimmune reactions that occur in the remote period of traumatic brain injury. In this case, the secondary mobilization of melatonin excretion by the pineal gland is considered as an auxiliary, protective phenomenon, aimed at those dysregulative disorders that occur in the remote period of closed traumatic brain injury." {Credits 1}

{Credits 1} 🎪 Volodymyr Korshnyak, Dynamics of Brain-Specific Proteins and Melatonin Before and After Microwave Resonance Therapy in Patients with Aftereffects of Mild Brain Injury, International Journal of Neurologic Physical Therapy. Vol. 5, No. 1, 2019, pp. 1-4. © 2019 The Author(s). This is an open access article distributed under the Creative Commons Attribution License.